Formation of Warped Disks by Galactic Fly-by Encounters. I. Stellar Disks

Warped disks are almost ubiquitous among spiral galaxies. Here we revisit and test the `fly-by scenario' of warp formation, in which impulsive encounters between galaxies are responsible for warped disks. Based on N-body simulations, we investigate the morphological and kinematical evolution of the stellar component of disks when galaxies undergo fly-by interactions with adjacent dark matter halos. We find that the so-called `S'-shaped warps can be excited by fly-bys and sustained for even up to a few billion years, and that this scenario provides a cohesive explanation for several key observations. We show that disk warp properties are governed primarily by the following three parameters; (1) the impact parameter, i.e., the minimum distance between two halos, (2) the mass ratio between two halos, and (3) the incident angle of the fly-by perturber. The warp angle is tied up with all three parameters, yet the warp lifetime is particularly sensitive to the incident angle of the perturber. Interestingly, the modeled S-shaped warps are often non-symmetric depending on the incident angle. We speculate that the puzzling U- and L-shaped warps are geometrically superimposed S-types produced by successive fly-bys with different incident angles, including multiple interactions with a satellite on a highly elongated orbit.Comment: 16 pages, 13 figures, 3 tables. Accepted for publication in Ap

Microlensing Characterization of Wide-Separation Planets

With their excellent photometric precision and dramatic increase in monitoring frequency, future microlensing survey experiments are expected to be sensitive to very short time-scale, isolated events caused by free-floating and wide-separation planets with mass as low as a few lunar masses. We estimate the probability of measuring the Einstein radius \theta_E for bound and free-floating planets. We carry out detailed simulations of the planetary events expected in next-generation surveys and estimate the resulting uncertainty in \theta_E for these events. We show that, for main-sequence sources and Jupiter-mass planets, the caustic structure of wide-separation planets with projected separations of < 20 AU substantially increases the probability of measuring the dimensionless source size and thus determining \theta_E compared to the case of unbound planets. In this limit where the source is much smaller than the caustic, the effective cross-section to measure \theta_E to 10% is ~25% larger than the full width of the caustic. Measurement of the lens parallax is possible for low-mass planetary events by combined observations from the ground and a satellite located in an L2 orbit; this would complete the mass measurements for such wide-separation planets. Finally, short-duration events caused by bound planets can be routinely distinguished from those caused by free-floating planets for planet-star separations < 20 AU from either the deviations due to the planetary caustic or (more often) the low-amplitude bump from the magnification due to the parent star.Comment: 10 pages including 7 figures. ApJ, in pres

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization

Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals. Recent studies revealed that acquisition of brown characteristics by white adipocytes, termed “browning,” may positively contribute to cellular bioenergetics and metabolism homeostasis. The goal was to investigate the putative effects of natural antioxidant sulforaphane (1-isothiocyanate-4-methyl-sulfonyl butane; SFN) on browning of white adipocytes. Methods and Results: 3T3-L1 mature white adipocytes were treated with SFN for 48 h, and then the mitochondrial content, function, and energy utilization were assessed. SFN was found to induce 3T3-L1 adipocytes browning based on the increased mitochondrial content and activity of respiratory chain enzymes, whereas the mechanism involved the upregulation of nuclear factor E2-related factor 2/ sirtuin1/ peroxisome proliferator-activated receptor gamma coactivator 1 alpha signaling. SFN enhanced uncoupling protein 1 expression, a marker for brown adipocyte, leading to the decrease in cellular ATP. SFN also enhanced glucose uptake and oxidative utilization, lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Conclusion: SFN-induced browning of white adipocytes enhanced the utilization of cellular fuel, and the application of SFN is a promising strategy to combat obesity and obesity-related metabolic disorder

Resolving Microlens Blends Using Image Subtraction

Blended light is an important source of degeneracy in the characterization of microlensing events, particularly in binary-lens and high magnification events. We show how the techniques of image subtraction can be applied to form an image of the blend with the source removed. In many cases, it should be possible to construct images with very high signal-to-noise ratio. Analysis of these images can help distinguish between competing models that have different blend fractions, and in some cases should allow direct detection of the lens.Comment: title changed, accepted version (including one figure), to appear in the Astrophysical Journal (Feb, 2002

A theorem on central velocity dispersions

It is shown that, if the tracer population is supported by a spherical dark halo with a core or a cusp diverging more slowly than that of a singular isothermal sphere, the logarithmic cusp slope 'g' of the tracers must be given exactly by g=2b where b is their velocity anisotropy parameter at the center unless the same tracers are dynamically cold at the center. If the halo cusp diverges faster than that of the singular isothermal sphere, the velocity dispersion of the tracers must diverge at the center too. In particular, if the logarithmic halo cusp slope is larger than two, the diverging velocity dispersion also traces the behavior of the potential. The implication of our theorem on projected quantities is also discussed. We argue that our theorem should be understood as a warning against interpreting results based on simplifying assumptions such as isotropy and spherical symmetry.Comment: submitted to Ap

Gravitational lensing by point masses on regular grid points

It is shown that gravitational lensing by point masses arranged in an infinitely extended regular lattice can be studied analytically using the Weierstrass functions. In particular, we draw the critical curves and the caustic networks for the lenses arranged in regular-polygonal -- square, equilateral triangle, regular hexagon -- grids. From this, the mean number of positive parity images as a function of the average optical depth is derived and compared to the case of the infinitely extended field of randomly distributed lenses. We find that the high degree of the symmetry in the lattice arrangement leads to a significant bias towards canceling of the shear caused by the neighboring lenses on a given lens position and lensing behaviour that is qualitatively distinct from the random star field. We also discuss some possible connections to more realistic lensing scenarios.Comment: to appear in Monthly Notices of RAS, including 17 figs, 1 appendix. High-res figs and F95 code used available upon reques

The Chang-Refsdal Lens Revisited

This paper provides a complete theoretical treatment of the point-mass lens perturbed by constant external shear, often called the Chang-Refsdal lens. We show that simple invariants exist for the products of the (complex) positions of the four images, as well as moment sums of their signed magnifications. The image topographies and equations of the caustics and critical curves are also studied. We derive the fully analytic expressions for precaustics, which are the loci of non-critical points that map to the caustics under the lens mapping. They constitute boundaries of the region in the image domain that maps onto the interior of the caustics. The areas under the critical curves, caustics and precaustics are all evaluated, which enables us to calculate the mean magnification of the source within the caustics. Additionally, the exact analytic expression for the magnification distribution for the source in the triangular caustics is derived, as well as a useful approximate expression. Finally, we find that the Chang-Refsdal lens with the convergence greater than unity can exhibit third-order critical behaviour, if the reduced shear is exactly equal to \sqrt{3}/2, and that the number of images for N-point masses with non-zero constant shear cannot be greater than 5N-1.Comment: to appear in MNRAS (including 6 figures, 3 appendices; v2 - minor update with corrected typos etc.

Association of the genetic polymorphisms of the ACE gene and the eNOS gene with lupus nephropathy in northern Chinese population

<p>Abstract</p> <p>Background</p> <p>It has been reported that some single nucleotide polymorphisms (SNPs) of the angiotensin converting enzyme (<it>ACE</it>) gene and the endothelial nitric oxide synthase (<it>eNOS</it>) gene are associated with the development of systemic lupus erythematosus (SLE) and the progression of nephropathy. The aim of this study was to evaluate the possible association between six SNPs (<it>A-5466C</it>, <it>T-3892C</it>, <it>A-240T</it>, <it>C1237T</it>, <it>G2215A </it>and <it>A2350G</it>) of the <it>ACE </it>gene and two SNPs (<it>T-786C </it>and <it>G894T</it>) of the <it>eNOS </it>gene with lupus nephropathy in a northern Chinese population.</p> <p>Methods</p> <p>In this study, 225 patients with lupus nephropathy were compared to 232 healthy controls, matched by gender, age and ethnicity. Following the extraction of genomic DNA from the leukocytes in the peripheral blood, the genotypes of the eight selected SNPs were determined by the method of PCR-RFLP; the haplotypes were inferred using PHASE 2.1. The associations between the SNPs and the risk of lupus nephropathy were analyzed using Chi-square test and Logistic regression with SPSS13.0 software.</p> <p>Results</p> <p>Statistically significant differences of the allele frequency distribution of three SNPs (<it>A-5466C</it>, <it>A2350G </it>and <it>G894T</it>) were observed between cases and controls (<it>P </it>< 0.05). Among the 53 haplotypes identified, the frequencies of five haplotypes (CTTCGA, ACTTAA, ACATGG, ACACGG and ATTCGA) were significantly different between cases and controls (<it>P </it>< 0.05).</p> <p>Conclusions</p> <p>Our study indicated an association between the risk of lupus nephropathy and the sequence variations of both the <it>ACE </it>gene and the <it>eNOS </it>gene, which may play an important role in the pathogenesis of lupus nephropathy in the northern Chinese population. Further studies are warranted to validate our findings.</p